Commonly used mouthwash could make saliva significantly more acidic, change microbes

The first study looking at the effect of chlorhexidine mouthwash on the entire oral microbiome has found its use significantly increases the abundance of lactate-producing bacteria that lower saliva pH, and may increase the risk of tooth damage. A team led by Dr Raul Bescos from the University of Plymouth's Faculty of Health gave a placebo mouthwash to subjects for seven days, followed by seven days of a chlorhexidine mouthwash.
At the end of each period, the researchers carried out an analysis of the abundance and diversity of the bacteria in the mouth -- the oral microbiome -- as well as measuring pH, saliva buffering capacity (the ability to neutralise acids in the mouth), lactate, glucose, nitrate and nitrite concentrations.

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