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The Translocation of Bacteria: Inflammatory Bowel Disease

person grabbing stomach in pain
Your eyes may be the window to the soul, but the mouth is the entrance to the whole body. The oral microbiome is second only to the gut microbiome in size, and all the oral bacteria can access the gut through the digestive tract. The mouth launches the regulation for our delicate ecosystem. The good news is that the gut can protect the body from invasion of oral pathogens whether through the lining of endothelial cells, stomach acid, probiotic bacteria, or immune cells. The bad news is that some pathogens still survive.

How pathogens invade and harm

Studies on mice and humans prove that oral bacteria can translocate to the gut and change its microbiota and immune defense.1 Thanks to the Human Microbiome Project, we’re learning a lot. A report in Genome Biology from the project found that oral cavity and stool bacteria overlapped in nearly half (45%) of the subjects 2...
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