The 3 C Medications Causing Gingival Hyperplasia
Some conditions can make people reluctant to show their smiles, such as tooth discoloration, missing teeth, and gingival hyperplasia, an overgrowth of the gums. Gingival hyperplasia affects not only aesthetics, but it also causes discomfort, alters one's speech, and hinders chewing. Certain medications, commonly referred to as the "three C's," are known to induce gingival hyperplasia: calcium channel blockers, cyclosporine, and anticonvulsants.
Calcium channel blockers
Calcium channel blockers (CCBs) are commonly prescribed for hypertension, angina, and arrhythmias. They can be divided into two classes: dihydropyridine (DHP) CCBs (e.g., amlodipine and nifedipine), which primarily cause vascular dilation; and non-dihydropyridine (non-DHP) CCBs (e.g., verapamil and diltiazem), which have effects on the heart.
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Calcium channel blockers
Calcium channel blockers (CCBs) are commonly prescribed for hypertension, angina, and arrhythmias. They can be divided into two classes: dihydropyridine (DHP) CCBs (e.g., amlodipine and nifedipine), which primarily cause vascular dilation; and non-dihydropyridine (non-DHP) CCBs (e.g., verapamil and diltiazem), which have effects on the heart.
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