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Biofilm Formation Resembles Urban Growth

Stack of $100 bills
As individual oral bacteria multiply and grow into a dense and sticky biofilm, such as the community that forms dental plaque, their growth patterns and dynamics mirror those seen in the growth of cities, according to researchers using super-resolution imaging technology with a computational algorithm at the University of Pennsylvania School of Dental Medicine. 
“We take this ‘satellite-level’ view, following hundreds of bacteria distributed on a surface from their initial colonization to biofilm formation,” said Hyun (Michel) Koo, DDS, MS, PhD, of the Department of Orthodontics and senior author of the work.

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